The Habana-Pinar del Río Highway crosses Artemisa from northeast to southwest. This main road runs also through 6 municipalities. The old Central Highway connects directly the municipal capitals of Bauta, Caimito, Guanajay, Candelaria and San Cristóbal with the provincial capital.
Artemisa occupies a central position in the territory, with excellent road communications with all the municipalities. It is located just 29 km from the center of the City of Havana.